Cell Line Lysates
ABclonal Technology PTPN1 Rabbit pAb
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which catalyzes the hydrolysis of phosphate monoesters on tyrosine residues. PTPs are key signaling molecules that regulate cellular processes such as growth, differentiation, the cell cycle, and oncogenic transformation. This PTP acts as a negative regulator of insulin signaling by dephosphorylating the insulin receptor kinase. It also dephosphorylates epidermal growth factor receptor kinase, JAK2, and TYK2 kinases, implicating it in cell growth control and responses to interferon. Two transcript variants encoding different isoforms have been identified for this gene.
ABclonal Technology CCR7 Rabbit pAb
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
Cayman Chemical Aszonapyron A 2.5mg
A meroditerpene fungal metabolite with diverse biological activities; inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively); active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation; active against P. falciparum in vitro (IC50 = 1.34 μg/ml)
Abcam Human ADCK4 knockout HeLa cell lysate.
Human ADCK4 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse liver tissue lysate - total protein (7 days).
Mouse liver tissue lysate - total protein (7 days).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse skin tissue lysate - total protein (0 days).
Mouse skin tissue lysate - total protein (0 days).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NDUFB5 knockout HeLa cell lysate.
Human NDUFB5 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.